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SPECTRAL

MOLECULAR

IMAGING

Home 2017-08-28T10:50:12+00:00

Create Quantitative 3D Images with MARS

Spectral Detectors

capture the color of x-rays

Medipix3 + High-Z

sensors increase x-ray conversion efficiency and reduce noise for optimal spatial, temporal and spectral (energy) resolution

Molecular Quantification

harness the color of x-rays

Recon+Processing Server

automatically produces a set of 3D image volumes containing each targeted element/compound (mg/mL) within minutes

Imaging Tools

visualize the color of x-rays

Vision Workstation+zSpace

interactive Virtual Reality system displays the element/compound 3D volumes for user-friendly sample evaluation and analysis

Pre-clinical spectral scanner

  • Medpix3 detectors bonded to high-Z sensors at 110 micron pitch with 8 energy bins per pixel and 2 ms frame readout
  • 120 kVp, 350 μA x-ray source with helical scan mode
  • Precision horizontal in vivo sample stage with gas lines, monitoring inputs and temperature sensors
  • Iterative reconstruction and processing algorithms quantify the concentration of elements and compounds in mg/mL
  • Visualization workstation with HP Zvr 3D virtual reality display for image analysis

Download the brochure

Molecular imaging without radiotracers

MARS promises to revolutionize diagnostic imaging by quantifying the elements and compounds of a sample in a single scan. It is the first commercially available 3D spectral (multi-energy) scanner to produce in vivo images with anatomic and molecular quantification at a fraction of the cost, time, and radiation dose of traditional molecular imaging, such as PET or SPECT.

The Medipix spectral x-ray detector technology was originally developed at CERN for the LHC and modified for medical applications; it is the result of 20+ years of collaborative innovation.

Our customers

My lab is pleased to feature the MARS photon-counting micro-CT in our research and development of targeted nanoparticle imaging probes for contrast-enhanced CT and quantitative molecular imaging with spectral (multi-energy) CT.

The MARS system is the only product on the market that enables my cutting-edge research to move forward as fast as possible. We are able to transition seamlessly between translation studies spanning from imaging phantoms to in vivo murine models.

Prof Ryan K. Roeder, University of Notre Dame

Our research horizons keep expanding as we learn more possibilities enabled by our MARS photon-counting micro-CT: from living histology to measuring drug delivery.  Using a new cutting-edge molecular imaging technology that is also quantitative has meant we are sought after as research partners by local and international collaborators.

Our grant funding success rate has increased. This is because we have the opportunity to make novel advances towards answering  hitherto unsolved medical research questions.  The non-destructive methodology used for these advances made in the laboratory is designed for translation to human imaging.

Assoc Prof Nigel Anderson, University of Otago

My lab is blessed to have the latest MARS photon-counting micro-CT scanner. This spectral (multi-energy) CT will be used  for preclinical research and development and translation to clinical applications such as targeted nanoparticle imaging and quantitative molecular imaging.

The MARS system is the only product in the market that enables important investigations with photon-counting detectors and redefines the state of the art.

Chair Professor Ge Wang, Rensselaer Polytechnic University