Create Quantitative 3D Images with MARS

Spectral Detectors

capture the color of x-rays

Medipix3 + High-Z

sensors increase x-ray conversion efficiency and reduce noise for optimal spatial, temporal and spectral (energy) resolution

Molecular Quantification

harness the color of x-rays

Recon+Processing Server

automatically produces a set of 3D image volumes containing each targeted element/compound (mg/mL) within minutes

Imaging Tools

visualize the color of x-rays

Vision Workstation+zSpace

interactive Virtual Reality system displays the element/compound 3D volumes for user-friendly sample evaluation and analysis

Molecular Imaging Without Radiotracers

MARS promises to revolutionize diagnostic imaging by quantifying the elements and compounds of a sample in a single scan. It is the first commercially available 3D spectral (multi-energy) scanner to produce in vivo images with anatomic and molecular quantification at a fraction of the cost, time, and radiation dose of traditional molecular imaging, such as PET or SPECT.

The Medipix3 spectral x-ray detector technology was originally developed at CERN for the LHC and modified medical applications; it is the result of 20+ years of collaborative innovation.

System Overview

  • Pre-clinical spectral scanner with 1, 3 or 5 chip Medpix3RX detector(s)
  • High-Z sensor bonded at 110 micron pixel pitch, 8 energy bins and 2 ms readout
  • 60 to 120 kVp, 1 to 350 mA x-ray source with helical scan mode
  • Horizontal in vivo sample stage with gas lines, monitoring inputs and temperature sensors
  • Iterative reconstruction and quantification algorithms resolve elements and compounds down to 1 mg/mL
  • Visualization workstation with zSpace 3D virtual reality for image analysis

Pretty Nice, What Else You Got Though?

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